Fig 1 shows immunohistochemical staining of SMA in the tumor stroma and the corresponding image obtained with DIA. The myofibroblastic stromal reaction was statistically greater in grade 2 and 3 tumors (p = 0.029). Strong myofibroblastic reaction was found in 51.5, 61.03, and 24% of tumors in grades 3, 2 and 1, respectively. In contrast, no significant relationship was observed between SMA stromal expression and other clinicopathological features. Table 2 summarizes these results. Here, SMN1 is linked to neoplasm.