As shown from Figure 2a-b and Supplementary Figure 1a-b, elevated FPR (p=0.014), Fib (p=0.002), PLR (p<0.001) and low AFR (p<0.001), pAlb (p=0.019), Alb (p=0.003) and LMR (p=0.040) were observed in right-sided mCRC in comparison with the left-sided cancer. The gene discussed is FBL; the disease is cancer.