For example, quinidine can be applied to treat KCNT1‐positive epilepsy,41, 42 and retigabine is utilized for KCNQ2‐positive epilepsy.43, 44 We suggested that zonisamide might be a precision treatment for epilepsy patients with NIPA2 loss‐of‐function mutation. The gene discussed is KCNT1; the disease is epilepsy.