To confirm the activation of Notch1 signalling by KK‐LC‐1 in liver cancer, we treated Huh7 cells with 5 μmol/L of N‐[N‐(3,5‐difluorophenacetyl)‐L‐alanyl]‐S‐phenylglycine t‐butylester (DAPT; Selleck, Houston, TX, USA) for three days to suppress the release of NICD1. Here, NOTCH1 is linked to liver cancer.