IL10 and autoimmune polyendocrinopathy: Bertone et al. found that APS had an average of 3,000 ng/mL of IL-10 compared to an average of 970 ng/mL of IL-10 in serum, resulting in a 3.4-fold difference, whereas we found that serum, ACS, and APS all contained ~250 pg/mL of IL-10 (15).