Interestingly, our transcriptomic data of R. conorii-infected THP-1 macrophages also revealed that RRAD (Ras-related glycolysis inhibitor and calcium channel regulator), belongs to one of the most upregulated genes at 1 h post-infection (unpublished results), which further supports the idea of a reduction in host glycolytic activity at an early stage of infection of THP-1 cells with R. conorii. Here, RRAD is linked to infection.