F3 and cancer: In other cancer-related examples, the expression of oncogenes such as mutant KRAS (147) or HRAS (148) modulates the composition of exosomes, and cytotoxic chemotherapy induces expression of phosphatidyl serine and tissue factor in MPs (149), and ERBB2/Her2 oncogene overexpression in EVs mediates transformation toward a malignant phenotype (150).