C4B and glaucoma: Interestingly, it also associates with decreased CH, CRF and IOPg (β = −0.29 SD, P = 3.1 × 10−12, β = −0.30 SD, P = 7.9 × 10−13 and β = −0.18 SD, P = 1.7 × 10−5, respectively) while not affecting glaucoma risk (OR = 0.92, CI = (0.82;1.03), P = 0.15).