Grade 3/4 treatment-emergent AEs observed in >1 patient included ALT elevation, AST elevation (n = 8 each); colitis (n = 4); fatigue (n = 3); anemia, confusional state, hyperglycemia, hyponatremia, hypotension, pruritus, and urinary tract infection (n = 2 each). The gene discussed is GPT; the disease is colitis.