Interestingly, the coding gene of Prdm1 that is associated with various cancer developments [11, 37–39, 41–43] exhibited the high expression level only in lymphoma (Additional file 2: Figure S4), even though all samples included PRDM1 in A compartment (Additional file 1: Table S5) enriched in TAD boundaries (Fig. 6a). This evidence concerns the gene PRDM1 and cancer.