LOX-1 and CD68 were higher in ischemic heart disease with T2DM than in those patients without T2DM and control patients, and were associated as a cardiovascular risk factor of ischemic heart disease and the severity of CAD, suggesting the importance of EAT in the coronary atherosclerosis among patients with T2DM. The gene discussed is OLR1; the disease is coronary atherosclerosis.