The mRNA expression of LOX-1, CL-P1, CD68 and CD11c in EAT were significantly higher in IHD-T2DM patients when compared with IHD-NoT2DM (P < 0.01) and control patients (P < 0.01) (Fig. 1a, b, e and g, respectively). Here, ITGAX is linked to type 2 diabetes mellitus.