A wide range of alterations to glycans have been observed in prostate cancer, including changes to PSA glycosylation, increased sialylation and fucosylation, increased O-GlcNacylation, the emergence of cryptic and branched N-glyans, and changes to galectins and proteoglycans [22,23,24] (see Tables 1–3 for more details). The gene discussed is KLK3; the disease is prostate carcinoma.