Along our finding that describes increased cell death caused by p53 induction after TCTP down-regulation, there has been a report that TCTP overexpression increases glioma cell proliferation and tumor growth of xenograft models by enhancing β-catenin association with TCF-4, thereby increasing TCF-4/β-catenin transcriptional activity [10]. This evidence concerns the gene TP53 and central nervous system cancer.