Early experiments demonstrated that typical ‘AHR-core’ genes (genes consistently upregulated by AHR activation, including multiple xenobiotic metabolism enzymes such as Cyp1a1 and Cyp2a1 [15,16]) were induced in experimental autoimmune encephalomyelitis (EAE) mice treated with LAQ [9]. This evidence concerns the gene AHR and experimental autoimmune encephalomyelitis.