BGLAP and osteoarthritis: A recent study indicates that Abs from chondrocytes may contribute to the pathogenic process of cartilage calcification in aging patients with osteoarthritis.15 However, it is unclear whether oxidative stress can increase the production of Abs and whether Abs can regulate the expression of calcification‐related genes, such as ALP, osteocalcin (OCN), Runt‐related transcription factor 2 (RUNX2) and collagen II (COL‐II) remain unclear.