The c.582‐2A>T mutation of the PRPH2 gene was verified to be heterozygous in the proband (pedigree II: 1; Figure 1D), while we revealed the wild‐type gene in the proband's daughter without RP symptoms till test at the ages of 30 (pedigree III: 1; Figure 1E), and the proband's wife had two copies of the wild‐type allele and a normal phenotype (pedigree II: 2; Figure 1F). Here, PRPH2 is linked to retinitis pigmentosa 1.