TF and abdominal aortic aneurysm: Interestingly, recent genome-wide association studies meta-analysis revealed a novel risk locus for abdominal aortic aneurysm within the ERG gene itself.48 Further studies will determine the functional role of noncoding variants associated with ERG enhancers, and will provide crucial insight into the contribution of ERG, cooperative TF and cofactor binding in complex disease susceptibility.