Hypoglycaemia, primarily associated with diabetes therapies, particularly insulin, is common in T2D,4, 5 and increases with age and longer duration of diabetes.6 Non‐severe episodes are associated with increased utilization of healthcare services and loss of work time,7, 8, 9 as well as impairment of quality of life; prevention of these episodes is therefore important. The gene discussed is INS; the disease is type 2 diabetes mellitus.