The transcription of Naips is regulated by the transcription factor IRF‐8.151 NLRC4 is implicated in the exacerbation of psoriatic lesions,152 and NLRP4 mutation is associated with exacerbation of asthma in smoking adults.153 Polymorphisms of NACHT‐LRR in NLRP12 and the promoter regions of NLRC4 and NLRP1 are associated with atopic dermatitis.113 The elusive other inflammasomes remain of outstanding interest. Here, NLRC4 is linked to asthma.