TUG1 and liver dysplastic nodule: TUG1 is significantly repressed in the podocytes of diabetic mice by rescuing PPARγ coactivator α (PGC-1α) expression, which is an important member of the nuclear receptor superfamily and well known to have an important role in mitochondrial bioenergetics and respiration [62, 63], and ameliorating the courses of DN, for regulating glomerular MCs proliferation, cell cycle, and diabetic glomerular ECM synthesis [64–66].