GABRA1 and GABRA2 are the components of the heteropentameric receptor for GABA, receptor of GABA (gamma-aminobutyric acid) that is an important inhibitory neurotransmitter in vertebrate brain and plays an essential role in the treatment of insomnia by inhibiting brain neurotransmitters excitement [44]. The gene discussed is GABRA2; the disease is insomnia measurement.