We analyzed the BSL male sub-cohort pro-inflammatory genes in T2D and CJP, and found only 3 inflammatory genes (LUM, WISP2, ARTN) with sex-dimorphic expression at comparable effect sizes in either T2D or CJP with respect to BSL (Figure 4B) suggesting that the pro-inflammatory gene signature is unlikely to be caused solely by a subset of donors in BSL that are suffering from inflammatory conditions unreported in the clinical record. This evidence concerns the gene CCN5 and type 2 diabetes mellitus.