Additionally spaghetti plots of individual mice in each of the treatment groups showed complete regression in 9/10 mice in the CTX + IL-1α-NP treatment group (Fig. 6B) compared to no tumor regression in the CTX + IL-1α-NP + anti-CD4 (Fig. 6C) and CTX + IL-1α-NP + anti-CD8 (Fig. 6D) treatment groups. This evidence concerns the gene CD8A and neoplasm.