Notably, the majority of predicted mRNA being targets of more than one miRNA, like CDK6, DCBLD2, GOLT1B (Golgi transport 1B), GTF2F2 (general transcription factor IIF subunit 2), HES7 (hes family bHLH transcription factor 7), MBP (myelin basic protein), PMAIP1 and PPP3CA, are engaged in cancer-related signaling pathways (reviewed in [71]). Here, HES7 is linked to cancer.