ABCC10 and lung carcinoma: We found that genetic variation in ABCC10 (rs2125739) was associated with the cytotoxicity of docetaxel in 18 lung cancer cell lines and this was confirmed by CRISPR-based genome editing, suggesting that the ABCC10 genotype may influence the ABCC10/MRP7 ability to deliver docetaxel and the cytoplasmic drug concentration of docetaxel.