APOA5 and coronary artery disorder: The Triglyceride Coronary Disease Genetics Consortium and Emerging Risk Factor Collaboration assessed the −1131T>C (rs662799) promoter polymorphism of the apoA-V (APOA5) gene in relation to TG concentration, several other risk factors, and risk of CHD.147 −1131T>C was modestly associated with lower HDL-C, lower apoA-I, and higher apoB, and strongly associated with elevated TG.