APOA1 and myocardial infarction: performed an MRT by identifying genetic variants associated independently with either apo(a) KIV2 number (rs2457564) or apo(a) concentration (rs3777392) in the Pakistan Risk of Myocardial Infarction Study (PROMIS).140 Genetic data from 60,801 CHD cases and 123,504 controls from the CARDIoGRAMplusC4D consortium revealed that the OR for MI was 0.96 per 1SD increment of apo(a) KIV2 number, while an OR of 1.27 was observed per 1SD increment of apo(a) concentration.