Several studies confirm that non-HDL-C is superior to LDL-C in predicting CHD.151,169 In a prospective study participants with high non-HDL-C concentrations were at increased CHD risk, independent of LDL-C concentrations.170 An analysis of the treating to new targets (TNT) and Incremental Decrease in End Points Through Aggressive Lipid Lowering (IDEAL) trials found that on-treatment, concentrations of non-HDL-C and apoB100 were better predictors of CVD risk than LDL-C.171 Puri et al. Here, APOB is linked to coronary artery disorder.