TFEB and neuroblastoma: In this study, by using the human neuroblastoma cell line SH-SY5Y, which is a widely used cell model in the study of autophagic pathways and neurodegeneration [39,40,41], we confirmed that curcumin has an inhibitory effect on mTORC1 and promotes both lysosomal functions and autophagy by inducing TFEB nuclear translocation.