PINK1 and Parkinson disease: Several important genes including PARK7 (encoding DJ‐1), α‐synuclein, parkin, PINK1, or LRRK2 have pathogenic mutations in PD which cause defects in mitochondrial dynamics and function.36 Specifically, mutation of α‐synuclein leads to its aggregation and these α‐synuclein aggregates delay fusion of phagosomes with lysosomes during the mitophagic process.