LYVE1 and rheumatoid arthritis: Exosomal lymphatic vessel endothelial hyaluronic acid receptor-1 (LYVE-1) was very recently reported to be a candidate marker of RA activity by a 2D-LC-MS/MS (two-dimensional liquid chromatography-tandem mass spectrometry) analysis of serum exosomal proteins from RA patients with complete remission and those with non-complete remission [19].