DPP4 and familial partial lipodystrophy, Dunnigan type: The hypothesis is partly supported by some bench studies [5, 7], by a clinical study evaluating DPP4 levels in patients with familial partial lipodystrophy type 2 (an inherited disease characterized by lack of SAT and fat deposition in VAT and ectopic sites) [26] and also by the knowledge that SAT is a determinant of metabolic health [27].