CHEK1 and cancer: Furthermore, inhibition of CHEK1 expression by UCN-01, CEP-3891 (Zhu et al., 2018), AZD7762, or LY2606368 inhibitors (Manic et al., 2017) can prevent the proliferation of cancer cells (Bryant, Rawlinson & Massey, 2014; Schuler et al., 2017).