AFP and Cirrhosis: In the subset of patients without cirrhosis, the 1-, 3- and 5-year OS rate for patients with low or high serum AFP level was 57.9%, 32.6% and 22% or 35.20%, 19.4% and 16.1%, respectively (P = 0.049, Fig. 2c), while for patients with low or high serum TBIL level it became 49.4%, 28% and 19.9% or 23.1%, 11.5% and 11.5%, respectively (P = 0.006, Fig. 2d).