Antioxidant-related biomarkers [SOD, glucose 6 phosphate dehydrogenase (G6PD), glutathione peroxidase (GPx), and CAT] showed statistically significant change, whereas total antioxidant status (TAS) and thiols did not show statistically significant change in patients with PD compared to controls. The gene discussed is G6PD; the disease is Parkinson disease.