The strong positivity of antimitochondrial antibodies was consistent with primary biliary cirrhosis and positive ANA along with elevated aspartate aminotransferase (AST) and alanine aminotransferase (ALT) were suggestive of AIH; but clinical symptoms of acute liver injury did not present.47 A 20-year-old woman and a 47-year-old man with RRMS treated with IFN-β1a presented with elevated liver function tests. This evidence concerns the gene GPT and primary biliary cholangitis.