LPLUNC1 also regulates the NPC cell radioresponse by inhibiting VTN-induced activation of the ataxia telangiectasia mutated kinase-Chk2 (ATM-Chk2) and ataxia telangiectasia and Rad3-related kinase-Chk1 (ATR-Chk1) pathways after ionising radiation (IR) [12]. The gene discussed is BPIFB1; the disease is Telangiectasia.