17 transcriptional target genes of NUCKS1 were coexpressed in the Mediumpurple2 module (Fig. 5B), including EP300, a network hub of the module whose expression was significantly increased in the striatum of PD patients (Z-score = 3.52, FDR = 0.029; Supplementary Table S1). The gene discussed is NUCKS1; the disease is Parkinson disease.