CDK1 and melanoma: In order to verify this finding, we studied publicly available data measuring transcriptomic effects of perturbing CDK1, obtained from two independent microarray experiments (GSE31534 and GSE31912) in an RNAi screen study that profiled gene expression in response to CDK1 knockdown in A375 (a human melanoma skin cell line) and MCF7 (a human breast cancer cell line)33.