Nevertheless, top SNPs of both KCNK3, suggested in astrocytes of temporal lobe epilepsy patients’ hippocampus85, and MAPRE3, implicated in dendritic spine morphology and synaptic plasticity in mature hippocampal neurons86, have affected their expression levels only in the DLPFC or cortex in our results but not in the hippocampus. Here, KCNK3 is linked to temporal lobe epilepsy.