Whereafter, MIR100HG was been showed to be dysregulated and function as tumor promoter or suppressor in human cancers including lung cancer [26], breast cancer [3,11,22], colorectal cancer [10], bladder cancer [1,23], cervical cancer [16], osteosarcoma [18], pancreatic ductal adenocarcinoma [14] head and neck squamous cell carcinoma, [24] and acute megakaryoblastic leukemia [7]. Here, MIR100HG is linked to acute megakaryoblastic leukemia.