In contrast, Gata6 expression in the epidermis is limited to a population of SD/SG progenitors in the developing HF and to the JZ, upper SG, and part of the infundibulum in adult skin (Figs 2A and 6A, and EV2A–C; Donati et al, 2017). This evidence concerns the gene GATA6 and hydrops fetalis.