Tumors from bazedoxifene‐treated Cdx2CreERT2; Apcflox and Lgr5CreERT2; Apcflox mice also showed reduced levels of the STAT3‐target gene bmi‐1 (Fig 5H and data not shown), encoding a polycomb repressor component that suppresses expression of cell cycle inhibitors, and therefore restricts intestinal tumor growth in Lgr5CreERT2; Apcflox; bmi‐1+/− mice (Fig 6A; Phesse et al, 2014). This evidence concerns the gene STAT3 and neoplasm.