Consistent with our observations in the Cdx2CreERT2; Apcflox colon cancer model, immunohistochemical analysis of tumors from bazedoxifene‐treated Lgr5CreERT2; Apcflox mice revealed a reduction in nuclear pSTAT3 and Ki67 staining that coincided with augmented TUNEL staining (Fig EV4). The gene discussed is MKI67; the disease is malignant colon neoplasm.