We next ascertained that the striking anti‐tumor effect of bazedoxifene treatment also extended to the epithelium of the small intestine, which is also susceptible to the therapeutic benefit conferred by inhibition of the IL11/STAT3 signaling axis at the level of the gp130‐associated JAK1/2 kinases (Phesse et al, 2014). The gene discussed is JAK1; the disease is neoplasm.