Using the anti-DYRK1A antibody 7D10 (named after α-DYRK1A-Cter) targeting the C-terminal region of DYRK1A, we observed decreased levels of DYRK1A in AD patients compared to controls (p < 0.05) (Additional file 1: Figure 1A,B). The gene discussed is DYRK1A; the disease is Alzheimer disease.