HER2 staining was observed in the cytoplasmic membrane of the cancer cells in 16 cases (IHC 0: 36 cases, IHC 1+: 43 cases, IHC 2+ with FISH negative: 5 cases, IHC 2+ with FISH positive: 3 cases and IHC 3+: 13 cases), with the positive rate 81.3% vs. 3.6% in NGAHIC-positive and NGAHIC-negative, respectively. Here, ERBB2 is linked to cancer.