Depression (p = 0.045), triglycerides (p = < 0.001) and hs-CRP (p = 0.021) were negatively associated with HDL-cholesterol levels, whereas female sex (p < 0.001), age (p = 0.005) and total cholesterol (p < 0.001) were positively associated with HDL-cholesterol levels in 171 patients (Table 4). The gene discussed is CRP; the disease is major depressive disorder.