SOAT1 and cancer: Network pharmacology indicated that the potential targets of emodin regulating N2 neutrophils were primarily associated with the “inflammatory response”, “signal transduction”, “cell proliferation”, “innate immune response” and “negative regulation of apoptotic process, indicating a function of emodin targeting multi-protein network, such as “Toll-like receptor signaling pathway”, “Jak-STAT signaling pathway” and “Cytokine-cytokine receptor interaction”, whereby it regulates neutrophil phenotypes to maintain system homeostasis for cancer prevention.