MAPK3 and neoplasm: The upregulation of certain members of the Rab family (such as Rab25, Rab5 and Rab11) in carcinogenic cells induces tumorigenesis by increasing cell proliferation and migration, via the activation of the Akt/mTORC1, extracellular signal-regulated kinase 1 (ERK1), and Wnt/β-catenin pathways, as well as inhibits tumor cell apoptosis via the decrease of Bak and Bax expression [24,26].