Furthermore, we analyzed if the protein products of genes differentially expressed with weight loss in SAT are similarly regulated in serum, and if gene expression and protein levels are related to body mass index (BMI) and established clinical markers of lipid and glucose metabolism (high density lipoprotein [HDL]-cholesterol, low density lipoprotein [LDL]-cholesterol, insulin, homeostatic model assessment for insulin resistance [HOMA-IR] values, and C-reactive protein [CRP]). This evidence concerns the gene CRP and Insulin resistance.