INS and Cirrhosis: Participants with cirrhosis had higher baseline insulin and HOMA-IR than non-cirrhotic patients in the RBV-sparing group (HOMA-IR mean difference 2.2, 95% CI 0.58–3.8, p = 0.01; insulin mean difference 52.5, 95% CI 8.5–96.4, p = 0.02).