LMNA and progeroid syndrome: In order to analyze the specific contribution of different cell types to the vascular pathology of progeria, we bred LmnaLCS/LCSTie2Cre+/tg and LmnaLCS/LCSSM22αCre+/tg mice, which respectively express progerin specifically in endothelial cells (ECs) and vascular smooth muscle cells (VSMCs).