Numerous studies have since tried to isolate CSCs from RCC 10, 11, 12, 13, 14, with CD105, ALDH1, OCT4, CD133, and CXCR4 reported as markers of cancer stem‐like cells from RCC 5, 11, 15, 16, 17, 18, 19. The gene discussed is POU5F1; the disease is renal cell carcinoma.