The CXCL10 (IP-10)/CXCR3 axis of inflammatory mediators is one of the most important chemokine axes and has been proven to be a lymphocyte‐associated metastasis mediator in several tumors [40], although in one, report serum levels of IP-10 were of measureable concentration but did not differ between the control and CRC groups [41]. This evidence concerns the gene CXCL10 and colorectal carcinoma.